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Juan Borrego-Carazo, Carles Sanchez, David Castells, Jordi Carrabina, & Debora Gil. (2023). BronchoPose: an analysis of data and model configuration for vision-based bronchoscopy pose estimation. CMPB - Computer Methods and Programs in Biomedicine, 228, 107241.
Abstract: Vision-based bronchoscopy (VB) models require the registration of the virtual lung model with the frames from the video bronchoscopy to provide effective guidance during the biopsy. The registration can be achieved by either tracking the position and orientation of the bronchoscopy camera or by calibrating its deviation from the pose (position and orientation) simulated in the virtual lung model. Recent advances in neural networks and temporal image processing have provided new opportunities for guided bronchoscopy. However, such progress has been hindered by the lack of comparative experimental conditions.
In the present paper, we share a novel synthetic dataset allowing for a fair comparison of methods. Moreover, this paper investigates several neural network architectures for the learning of temporal information at different levels of subject personalization. In order to improve orientation measurement, we also present a standardized comparison framework and a novel metric for camera orientation learning. Results on the dataset show that the proposed metric and architectures, as well as the standardized conditions, provide notable improvements to current state-of-the-art camera pose estimation in video bronchoscopy.
Keywords: Videobronchoscopy guiding; Deep learning; Architecture optimization; Datasets; Standardized evaluation framework; Pose estimation
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Oriol Ramos Terrades, Albert Berenguel, & Debora Gil. (2022). A Flexible Outlier Detector Based on a Topology Given by Graph Communities. BDR - Big Data Research, 29, 100332.
Abstract: Outlier detection is essential for optimal performance of machine learning methods and statistical predictive models. Their detection is especially determinant in small sample size unbalanced problems, since in such settings outliers become highly influential and significantly bias models. This particular experimental settings are usual in medical applications, like diagnosis of rare pathologies, outcome of experimental personalized treatments or pandemic emergencies. In contrast to population-based methods, neighborhood based local approaches compute an outlier score from the neighbors of each sample, are simple flexible methods that have the potential to perform well in small sample size unbalanced problems. A main concern of local approaches is the impact that the computation of each sample neighborhood has on the method performance. Most approaches use a distance in the feature space to define a single neighborhood that requires careful selection of several parameters, like the number of neighbors.
This work presents a local approach based on a local measure of the heterogeneity of sample labels in the feature space considered as a topological manifold. Topology is computed using the communities of a weighted graph codifying mutual nearest neighbors in the feature space. This way, we provide with a set of multiple neighborhoods able to describe the structure of complex spaces without parameter fine tuning. The extensive experiments on real-world and synthetic data sets show that our approach outperforms, both, local and global strategies in multi and single view settings.
Keywords: Classification algorithms; Detection algorithms; Description of feature space local structure; Graph communities; Machine learning algorithms; Outlier detectors
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Mireia Sole, Joan Blanco, Debora Gil, Oliver Valero, B. Cardenas, G. Fonseka, et al. (2022). Time to match; when do homologous chromosomes become closer? CHRO - Chromosoma, .
Abstract: In most eukaryotes, pairing of homologous chromosomes is an essential feature of meiosis that ensures homologous recombination and segregation. However, when the pairing process begins, it is still under investigation. Contrasting data exists in Mus musculus, since both leptotene DSB-dependent and preleptotene DSB-independent mechanisms have been described. To unravel this contention, we examined homologous pairing in pre-meiotic and meiotic Mus musculus cells using a threedimensional fuorescence in situ hybridization-based protocol, which enables the analysis of the entire karyotype using DNA painting probes. Our data establishes in an unambiguously manner that 73.83% of homologous chromosomes are already paired at premeiotic stages (spermatogonia-early preleptotene spermatocytes). The percentage of paired homologous chromosomes increases to 84.60% at mid-preleptotene-zygotene stage, reaching 100% at pachytene stage. Importantly, our results demonstrate a high percentage of homologous pairing observed before the onset of meiosis; this pairing does not occur randomly, as the percentage was higher than that observed in somatic cells (19.47%) and between nonhomologous chromosomes (41.1%). Finally, we have also observed that premeiotic homologous pairing is asynchronous and independent of the chromosome size, GC content, or presence of NOR regions.
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Debora Gil, Aura Hernandez-Sabate, Julien Enconniere, Saryani Asmayawati, Pau Folch, Juan Borrego-Carazo, et al. (2022). E-Pilots: A System to Predict Hard Landing During the Approach Phase of Commercial Flights. ACCESS - IEEE Access, 10, 7489–7503.
Abstract: More than half of all commercial aircraft operation accidents could have been prevented by executing a go-around. Making timely decision to execute a go-around manoeuvre can potentially reduce overall aviation industry accident rate. In this paper, we describe a cockpit-deployable machine learning system to support flight crew go-around decision-making based on the prediction of a hard landing event.
This work presents a hybrid approach for hard landing prediction that uses features modelling temporal dependencies of aircraft variables as inputs to a neural network. Based on a large dataset of 58177 commercial flights, the results show that our approach has 85% of average sensitivity with 74% of average specificity at the go-around point. It follows that our approach is a cockpit-deployable recommendation system that outperforms existing approaches.
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David Castells, Vinh Ngo, Juan Borrego-Carazo, Marc Codina, Carles Sanchez, Debora Gil, et al. (2022). A Survey of FPGA-Based Vision Systems for Autonomous Cars. ACESS - IEEE Access, 10, 132525–132563.
Abstract: On the road to making self-driving cars a reality, academic and industrial researchers are working hard to continue to increase safety while meeting technical and regulatory constraints Understanding the surrounding environment is a fundamental task in self-driving cars. It requires combining complex computer vision algorithms. Although state-of-the-art algorithms achieve good accuracy, their implementations often require powerful computing platforms with high power consumption. In some cases, the processing speed does not meet real-time constraints. FPGA platforms are often used to implement a category of latency-critical algorithms that demand maximum performance and energy efficiency. Since self-driving car computer vision functions fall into this category, one could expect to see a wide adoption of FPGAs in autonomous cars. In this paper, we survey the computer vision FPGA-based works from the literature targeting automotive applications over the last decade. Based on the survey, we identify the strengths and weaknesses of FPGAs in this domain and future research opportunities and challenges.
Keywords: Autonomous automobile; Computer vision; field programmable gate arrays; reconfigurable architectures
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