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Author |
Frederic Sampedro; Sergio Escalera; Anna Domenech; Ignasi Carrio |
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Title |
Automatic Tumor Volume Segmentation in Whole-Body PET/CT Scans: A Supervised Learning Approach Source |
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Journal Article |
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Year |
2015 |
Publication |
Journal of Medical Imaging and Health Informatics |
Abbreviated Journal |
JMIHI |
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5 |
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2 |
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192-201 |
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CONTEXTUAL CLASSIFICATION; PET/CT; SUPERVISED LEARNING; TUMOR SEGMENTATION; WHOLE BODY |
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Whole-body 3D PET/CT tumoral volume segmentation provides relevant diagnostic and prognostic information in clinical oncology and nuclear medicine. Carrying out this procedure manually by a medical expert is time consuming and suffers from inter- and intra-observer variabilities. In this paper, a completely automatic approach to this task is presented. First, the problem is stated and described both in clinical and technological terms. Then, a novel supervised learning segmentation framework is introduced. The segmentation by learning approach is defined within a Cascade of Adaboost classifiers and a 3D contextual proposal of Multiscale Stacked Sequential Learning. Segmentation accuracy results on 200 Breast Cancer whole body PET/CT volumes show mean 49% sensitivity, 99.993% specificity and 39% Jaccard overlap Index, which represent good performance results both at the clinical and technological level. |
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HuPBA;MILAB |
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Admin @ si @ SED2015 |
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2584 |
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Author |
Frederic Sampedro; Anna Domenech; Sergio Escalera |
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Title |
Static and dynamic computational cancer spread quantification in whole body FDG-PET/CT scans |
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Journal Article |
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2014 |
Publication |
Journal of Medical Imaging and Health Informatics |
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JMIHI |
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4 |
Issue |
6 |
Pages |
825-831 |
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Keywords |
CANCER SPREAD; COMPUTER AIDED DIAGNOSIS; MEDICAL IMAGING; TUMOR QUANTIFICATION |
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Abstract |
In this work we address the computational cancer spread quantification scenario in whole body FDG-PET/CT scans. At the static level, this setting can be modeled as a clustering problem on the set of 3D connected components of the whole body PET tumoral segmentation mask carried out by nuclear medicine physicians. At the dynamic level, and ad-hoc algorithm is proposed in order to quantify the cancer spread time evolution which, when combined with other existing indicators, gives rise to the metabolic tumor volume-aggressiveness-spread time evolution chart, a novel tool that we claim that would prove useful in nuclear medicine and oncological clinical or research scenarios. Good performance results of the proposed methodologies both at the clinical and technological level are shown using a dataset of 48 segmented whole body FDG-PET/CT scans. |
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Admin @ si @ SDE2014b |
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2548 |
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Author |
Frederic Sampedro; Sergio Escalera; Anna Puig |
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Title |
Iterative Multiclass Multiscale Stacked Sequential Learning: definition and application to medical volume segmentation |
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Journal Article |
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Year |
2014 |
Publication |
Pattern Recognition Letters |
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PRL |
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46 |
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1-10 |
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Keywords |
Machine learning; Sequential learning; Multi-class problems; Contextual learning; Medical volume segmentation |
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In this work we present the iterative multi-class multi-scale stacked sequential learning framework (IMMSSL), a novel learning scheme that is particularly suited for medical volume segmentation applications. This model exploits the inherent voxel contextual information of the structures of interest in order to improve its segmentation performance results. Without any feature set or learning algorithm prior assumption, the proposed scheme directly seeks to learn the contextual properties of a region from the predicted classifications of previous classifiers within an iterative scheme. Performance results regarding segmentation accuracy in three two-class and multi-class medical volume datasets show a significant improvement with respect to state of the art alternatives. Due to its easiness of implementation and its independence of feature space and learning algorithm, the presented machine learning framework could be taken into consideration as a first choice in complex volume segmentation scenarios. |
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HuPBA;MILAB |
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no |
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Admin @ si @ SEP2014 |
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2550 |
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Author |
Daniel Sanchez; Miguel Angel Bautista; Sergio Escalera |
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Title |
HuPBA 8k+: Dataset and ECOC-GraphCut based Segmentation of Human Limbs |
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Journal Article |
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Year |
2015 |
Publication |
Neurocomputing |
Abbreviated Journal |
NEUCOM |
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Volume |
150 |
Issue |
A |
Pages |
173–188 |
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Human limb segmentation; ECOC; Graph-Cuts |
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Human multi-limb segmentation in RGB images has attracted a lot of interest in the research community because of the huge amount of possible applications in fields like Human-Computer Interaction, Surveillance, eHealth, or Gaming. Nevertheless, human multi-limb segmentation is a very hard task because of the changes in appearance produced by different points of view, clothing, lighting conditions, occlusions, and number of articulations of the human body. Furthermore, this huge pose variability makes the availability of large annotated datasets difficult. In this paper, we introduce the HuPBA8k+ dataset. The dataset contains more than 8000 labeled frames at pixel precision, including more than 120000 manually labeled samples of 14 different limbs. For completeness, the dataset is also labeled at frame-level with action annotations drawn from an 11 action dictionary which includes both single person actions and person-person interactive actions. Furthermore, we also propose a two-stage approach for the segmentation of human limbs. In a first stage, human limbs are trained using cascades of classifiers to be split in a tree-structure way, which is included in an Error-Correcting Output Codes (ECOC) framework to define a body-like probability map. This map is used to obtain a binary mask of the subject by means of GMM color modelling and GraphCuts theory. In a second stage, we embed a similar tree-structure in an ECOC framework to build a more accurate set of limb-like probability maps within the segmented user mask, that are fed to a multi-label GraphCut procedure to obtain final multi-limb segmentation. The methodology is tested on the novel HuPBA8k+ dataset, showing performance improvements in comparison to state-of-the-art approaches. In addition, a baseline of standard action recognition methods for the 11 actions categories of the novel dataset is also provided. |
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HuPBA;MILAB |
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Admin @ si @ SBE2015 |
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2552 |
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Author |
G. Zahnd; Simone Balocco; A. Serusclat; P. Moulin; M. Orkisz; D. Vray |
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Title |
Progressive attenuation of the longitudinal kinetics in the common carotid artery: preliminary in vivo assessment Ultrasound in Medicine and Biology |
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Journal Article |
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Year |
2015 |
Publication |
Ultrasound in Medicine and Biology |
Abbreviated Journal |
UMB |
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41 |
Issue |
1 |
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339-345 |
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Keywords |
Arterial stiffness; Atherosclerosis; Common carotid artery; Longitudinal kinetics; Motion tracking; Ultrasound imaging |
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Abstract |
Longitudinal kinetics (LOKI) of the arterial wall consists of the shearing motion of the intima-media complex over the adventitia layer in the direction parallel to the blood flow during the cardiac cycle. The aim of this study was to investigate the local variability of LOKI amplitude along the length of the vessel. By use of a previously validated motion-estimation framework, 35 in vivo longitudinal B-mode ultrasound cine loops of healthy common carotid arteries were analyzed. Results indicated that LOKI amplitude is progressively attenuated along the length of the artery, as it is larger in regions located on the proximal side of the image (i.e., toward the heart) and smaller in regions located on the distal side of the image (i.e., toward the head), with an average attenuation coefficient of -2.5 ± 2.0%/mm. Reported for the first time in this study, this phenomenon is likely to be of great importance in improving understanding of atherosclerosis mechanisms, and has the potential to be a novel index of arterial stiffness. |
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MILAB |
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Admin @ si @ ZBS2014 |
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2556 |
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