Abstract: Deep neural networks represent a compelling technique to tackle complex real-world problems, but are over-parameterized and often suffer from over- or under-confident estimates. Deep ensembles have shown better parameter estimations and often provide reliable uncertainty estimates that contribute to the robustness of the results. In this work, we propose a new metric to identify samples that are hard to classify. Our metric is defined as coincidence score for deep ensembles which measures the agreement of its individual models. The main hypothesis we rely on is that deep learning algorithms learn the low-loss samples better compared to large-loss samples. In order to compensate for this, we use controlled over-sampling on the identified ”hard” samples using proper data augmentation schemes to enable the models to learn those samples better. We validate the proposed metric using two public food datasets on different backbone architectures and show the improvements compared to the conventional deep neural network training using different performance metrics.

Abstract: Background and objective:An accurate segmentation of lung nodules in computed tomography images is a crucial step for the physical characterization of the tumour. Being often completely manually accomplished, nodule segmentation turns to be a tedious and time-consuming procedure and this represents a high obstacle in clinical practice. In this paper, we propose a novel Convolutional Neural Network for nodule segmentation that combines a light and efficient architecture with innovative loss function and segmentation strategy. Methods:In contrast to most of the standard end-to-end architectures for nodule segmentation, our network learns the context of the nodules by producing two masks representing all the background and secondary-important elements in the Computed Tomography scan. The nodule is detected by subtracting the context from the original scan image. Additionally, we introduce an asymmetric loss function that automatically compensates for potential errors in the nodule annotations. We trained and tested our Neural Network on the public LIDC-IDRI database, compared it with the state of the art and run a pseudo-Turing test between four radiologists and the network. Results:The results proved that the behaviour of the algorithm is very near to the human performance and its segmentation masks are almost indistinguishable from the ones made by the radiologists. Our method clearly outperforms the state of the art on CT nodule segmentation in terms of F1 score and IoU of and respectively. Conclusions: The main structure of the network ensures all the properties of the UNet architecture, while the Multi Convolutional Layers give a more accurate pattern recognition. The newly adopted solutions also increase the details on the border of the nodule, even under the noisiest conditions. This method can be applied now for single CT slice nodule segmentation and it represents a starting point for the future development of a fully automatic 3D segmentation software.