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Michal Drozdzal; Santiago Segui; Petia Radeva; Carolina Malagelada; Fernando Azpiroz; Jordi Vitria |
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Motility bar: a new tool for motility analysis of endoluminal videos |
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Journal Article |
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2015 |
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Computers in Biology and Medicine |
Abbreviated Journal |
CBM |
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65 |
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320-330 |
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Small intestine; Motility; WCE; Computer vision; Image classification |
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Wireless Capsule Endoscopy (WCE) provides a new perspective of the small intestine, since it enables, for the first time, visualization of the entire organ. However, the long visual video analysis time, due to the large number of data in a single WCE study, was an important factor impeding the widespread use of the capsule as a tool for intestinal abnormalities detection. Therefore, the introduction of WCE triggered a new field for the application of computational methods, and in particular, of computer vision. In this paper, we follow the computational approach and come up with a new perspective on the small intestine motility problem. Our approach consists of three steps: first, we review a tool for the visualization of the motility information contained in WCE video; second, we propose algorithms for the characterization of two motility building-blocks: contraction detector and lumen size estimation; finally, we introduce an approach to detect segments of stable motility behavior. Our claims are supported by an evaluation performed with 10 WCE videos, suggesting that our methods ably capture the intestinal motility information. |
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MILAB;MV |
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Admin @ si @ DSR2015 |
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2635 |
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Tadashi Araki; Nobutaka Ikeda; Nilanjan Dey; Sayan Chakraborty; Luca Saba; Dinesh Kumar; Elisa Cuadrado Godia; Xiaoyi Jiang; Ajay Gupta; Petia Radeva; John R. Laird; Andrew Nicolaides; Jasjit S. Suri |
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A comparative approach of four different image registration techniques for quantitative assessment of coronary artery calcium lesions using intravascular ultrasound |
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2015 |
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Computer Methods and Programs in Biomedicine |
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CMPB |
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118 |
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2 |
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158-172 |
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MILAB |
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Admin @ si @ AID2015 |
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2640 |
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Andres Traumann; Gholamreza Anbarjafari; Sergio Escalera |
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Title |
Accurate 3D Measurement Using Optical Depth Information |
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2015 |
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Electronic Letters |
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EL |
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51 |
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18 |
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1420-1422 |
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A novel three-dimensional measurement technique is proposed. The methodology consists in mapping from the screen coordinates reported by the optical camera to the real world, and integrating distance gradients from the beginning to the end point, while also minimising the error through fitting pixel locations to a smooth curve. The results demonstrate accuracy of less than half a centimetre using Microsoft Kinect II. |
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HuPBA;MILAB |
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Admin @ si @ TAE2015 |
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2647 |
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Carolina Malagelada; Michal Drozdzal; Santiago Segui; Sara Mendez; Jordi Vitria; Petia Radeva; Javier Santos; Anna Accarino; Juan R. Malagelada; Fernando Azpiroz |
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Classification of functional bowel disorders by objective physiological criteria based on endoluminal image analysis |
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2015 |
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American Journal of Physiology-Gastrointestinal and Liver Physiology |
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AJPGI |
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309 |
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6 |
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G413--G419 |
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Keywords |
capsule endoscopy; computer vision analysis; functional bowel disorders; intestinal motility; machine learning |
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We have previously developed an original method to evaluate small bowel motor function based on computer vision analysis of endoluminal images obtained by capsule endoscopy. Our aim was to demonstrate intestinal motor abnormalities in patients with functional bowel disorders by endoluminal vision analysis. Patients with functional bowel disorders (n = 205) and healthy subjects (n = 136) ingested the endoscopic capsule (Pillcam-SB2, Given-Imaging) after overnight fast and 45 min after gastric exit of the capsule a liquid meal (300 ml, 1 kcal/ml) was administered. Endoluminal image analysis was performed by computer vision and machine learning techniques to define the normal range and to identify clusters of abnormal function. After training the algorithm, we used 196 patients and 48 healthy subjects, completely naive, as test set. In the test set, 51 patients (26%) were detected outside the normal range (P < 0.001 vs. 3 healthy subjects) and clustered into hypo- and hyperdynamic subgroups compared with healthy subjects. Patients with hypodynamic behavior (n = 38) exhibited less luminal closure sequences (41 ± 2% of the recording time vs. 61 ± 2%; P < 0.001) and more static sequences (38 ± 3 vs. 20 ± 2%; P < 0.001); in contrast, patients with hyperdynamic behavior (n = 13) had an increased proportion of luminal closure sequences (73 ± 4 vs. 61 ± 2%; P = 0.029) and more high-motion sequences (3 ± 1 vs. 0.5 ± 0.1%; P < 0.001). Applying an original methodology, we have developed a novel classification of functional gut disorders based on objective, physiological criteria of small bowel function. |
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American Physiological Society |
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MILAB; OR;MV |
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Admin @ si @ MDS2015 |
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2666 |
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R.A.Bendezu; E.Barba; E.Burri; D.Cisternas; Carolina Malagelada; Santiago Segui; Anna Accarino; S.Quiroga; E.Monclus; I.Navazo |
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Title |
Intestinal gas content and distribution in health and in patients with functional gut symptoms |
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Journal Article |
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Year |
2015 |
Publication |
Neurogastroenterology & Motility |
Abbreviated Journal |
NEUMOT |
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27 |
Issue |
9 |
Pages |
1249-1257 |
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BACKGROUND:
The precise relation of intestinal gas to symptoms, particularly abdominal bloating and distension remains incompletely elucidated. Our aim was to define the normal values of intestinal gas volume and distribution and to identify abnormalities in relation to functional-type symptoms.
METHODS:
Abdominal computed tomography scans were evaluated in healthy subjects (n = 37) and in patients in three conditions: basal (when they were feeling well; n = 88), during an episode of abdominal distension (n = 82) and after a challenge diet (n = 24). Intestinal gas content and distribution were measured by an original analysis program. Identification of patients outside the normal range was performed by machine learning techniques (one-class classifier). Results are expressed as median (IQR) or mean ± SE, as appropriate.
KEY RESULTS:
In healthy subjects the gut contained 95 (71, 141) mL gas distributed along the entire lumen. No differences were detected between patients studied under asymptomatic basal conditions and healthy subjects. However, either during a spontaneous bloating episode or once challenged with a flatulogenic diet, luminal gas was found to be increased and/or abnormally distributed in about one-fourth of the patients. These patients detected outside the normal range by the classifier exhibited a significantly greater number of abnormal features than those within the normal range (3.7 ± 0.4 vs 0.4 ± 0.1; p < 0.001).
CONCLUSIONS & INFERENCES:
The analysis of a large cohort of subjects using original techniques provides unique and heretofore unavailable information on the volume and distribution of intestinal gas in normal conditions and in relation to functional gastrointestinal symptoms. |
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MILAB |
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Admin @ si @ BBB2015 |
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2667 |
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