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Simone Balocco; Carlo Gatta; Francesco Ciompi; A. Wahle; Petia Radeva; S. Carlier; G. Unal; E. Sanidas; J. Mauri; X. Carillo; T. Kovarnik; C. Wang; H. Chen; T. P. Exarchos; D. I. Fotiadis; F. Destrempes; G. Cloutier; Oriol Pujol; Marina Alberti; E. G. Mendizabal-Ruiz; M. Rivera; T. Aksoy; R. W. Downe; I. A. Kakadiaris |
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Title |
Standardized evaluation methodology and reference database for evaluating IVUS image segmentation |
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Journal Article |
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2014 |
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Computerized Medical Imaging and Graphics |
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CMIG |
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38 |
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2 |
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70-90 |
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IVUS (intravascular ultrasound); Evaluation framework; Algorithm comparison; Image segmentation |
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This paper describes an evaluation framework that allows a standardized and quantitative comparison of IVUS lumen and media segmentation algorithms. This framework has been introduced at the MICCAI 2011 Computing and Visualization for (Intra)Vascular Imaging (CVII) workshop, comparing the results of eight teams that participated.
We describe the available data-base comprising of multi-center, multi-vendor and multi-frequency IVUS datasets, their acquisition, the creation of the reference standard and the evaluation measures. The approaches address segmentation of the lumen, the media, or both borders; semi- or fully-automatic operation; and 2-D vs. 3-D methodology. Three performance measures for quantitative analysis have
been proposed. The results of the evaluation indicate that segmentation of the vessel lumen and media is possible with an accuracy that is comparable to manual annotation when semi-automatic methods are used, as well as encouraging results can be obtained also in case of fully-automatic segmentation. The analysis performed in this paper also highlights the challenges in IVUS segmentation that remains to be
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MILAB; LAMP; HuPBA; 600.046; 600.063; 600.079 |
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Admin @ si @ BGC2013 |
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2314 |
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Author ![sorted by Author field, ascending order (up)](http://refbase.cvc.uab.es/img/sort_asc.gif) |
Simone Balocco; Carlo Gatta; Marina Alberti; Xavier Carrillo; Juan Rigla; Petia Radeva |
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Relation between plaque type, plaque thickness, blood shear stress and plaque stress in coronary arteries assessed by X-ray Angiography and Intravascular Ultrasound |
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Journal Article |
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2012 |
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Medical Physics |
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MEDPHYS |
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39 |
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12 |
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7430-7445 |
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PMID 23231293
PURPOSE:
Atheromatic plaque progression is affected, among others phenomena, by biomechanical, biochemical, and physiological factors. In this paper, the authors introduce a novel framework able to provide both morphological (vessel radius, plaque thickness, and type) and biomechanical (wall shear stress and Von Mises stress) indices of coronary arteries.
METHODS:
First, the approach reconstructs the three-dimensional morphology of the vessel from intravascular ultrasound (IVUS) and Angiographic sequences, requiring minimal user interaction. Then, a computational pipeline allows to automatically assess fluid-dynamic and mechanical indices. Ten coronary arteries are analyzed illustrating the capabilities of the tool and confirming previous technical and clinical observations.
RESULTS:
The relations between the arterial indices obtained by IVUS measurement and simulations have been quantitatively analyzed along the whole surface of the artery, extending the analysis of the coronary arteries shown in previous state of the art studies. Additionally, for the first time in the literature, the framework allows the computation of the membrane stresses using a simplified mechanical model of the arterial wall.
CONCLUSIONS:
Circumferentially (within a given frame), statistical analysis shows an inverse relation between the wall shear stress and the plaque thickness. At the global level (comparing a frame within the entire vessel), it is observed that heavy plaque accumulations are in general calcified and are located in the areas of the vessel having high wall shear stress. Finally, in their experiments the inverse proportionality between fluid and structural stresses is observed. |
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MILAB |
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Admin @ si @BGA2012 |
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2170 |
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Author ![sorted by Author field, ascending order (up)](http://refbase.cvc.uab.es/img/sort_asc.gif) |
Simone Balocco; Carlo Gatta; Oriol Pujol; J. Mauri; Petia Radeva |
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SRBF: Speckle Reducing Bilateral Filtering |
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Journal Article |
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2010 |
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Ultrasound in Medicine and Biology |
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UMB |
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36 |
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8 |
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1353-1363 |
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Speckle noise negatively affects medical ultrasound image shape interpretation and boundary detection. Speckle removal filters are widely used to selectively remove speckle noise without destroying important image features to enhance object boundaries. In this article, a fully automatic bilateral filter tailored to ultrasound images is proposed. The edge preservation property is obtained by embedding noise statistics in the filter framework. Consequently, the filter is able to tackle the multiplicative behavior modulating the smoothing strength with respect to local statistics. The in silico experiments clearly showed that the speckle reducing bilateral filter (SRBF) has superior performances to most of the state of the art filtering methods. The filter is tested on 50 in vivo US images and its influence on a segmentation task is quantified. The results using SRBF filtered data sets show a superior performance to using oriented anisotropic diffusion filtered images. This improvement is due to the adaptive support of SRBF and the embedded noise statistics, yielding a more homogeneous smoothing. SRBF results in a fully automatic, fast and flexible algorithm potentially suitable in wide ranges of speckle noise sizes, for different medical applications (IVUS, B-mode, 3-D matrix array US). |
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MILAB;HUPBA |
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BCNPCL @ bcnpcl @ BGP2010 |
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1314 |
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Author ![sorted by Author field, ascending order (up)](http://refbase.cvc.uab.es/img/sort_asc.gif) |
Simone Balocco; Francesco Ciompi; Juan Rigla; Xavier Carrillo; J. Mauri; Petia Radeva |
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Title |
Assessment of intracoronary stent location and extension in intravascular ultrasound sequences |
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Journal Article |
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2019 |
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Medical Physics |
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MEDPHYS |
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46 |
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2 |
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484-493 |
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IVUS; malapposition; stent; ultrasound |
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PURPOSE:
An intraluminal coronary stent is a metal scaffold deployed in a stenotic artery during percutaneous coronary intervention (PCI). In order to have an effective deployment, a stent should be optimally placed with regard to anatomical structures such as bifurcations and stenoses. Intravascular ultrasound (IVUS) is a catheter-based imaging technique generally used for PCI guiding and assessing the correct placement of the stent. A novel approach that automatically detects the boundaries and the position of the stent along the IVUS pullback is presented. Such a technique aims at optimizing the stent deployment.
METHODS:
The method requires the identification of the stable frames of the sequence and the reliable detection of stent struts. Using these data, a measure of likelihood for a frame to contain a stent is computed. Then, a robust binary representation of the presence of the stent in the pullback is obtained applying an iterative and multiscale quantization of the signal to symbols using the Symbolic Aggregate approXimation algorithm.
RESULTS:
The technique was extensively validated on a set of 103 IVUS of sequences of in vivo coronary arteries containing metallic and bioabsorbable stents acquired through an international multicentric collaboration across five clinical centers. The method was able to detect the stent position with an overall F-measure of 86.4%, a Jaccard index score of 75% and a mean distance of 2.5 mm from manually annotated stent boundaries, and in bioabsorbable stents with an overall F-measure of 88.6%, a Jaccard score of 77.7 and a mean distance of 1.5 mm from manually annotated stent boundaries. Additionally, a map indicating the distance between the lumen and the stent along the pullback is created in order to show the angular sectors of the sequence in which the malapposition is present.
CONCLUSIONS:
Results obtained comparing the automatic results vs the manual annotation of two observers shows that the method approaches the interobserver variability. Similar performances are obtained on both metallic and bioabsorbable stents, showing the flexibility and robustness of the method. |
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MILAB; no proj |
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Admin @ si @ BCR2019 |
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3231 |
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Author ![sorted by Author field, ascending order (up)](http://refbase.cvc.uab.es/img/sort_asc.gif) |
Simone Balocco; O. Basset; G. Courbebaisse; E. Boni; Alejandro F. Frangi; P. Tortoli; C. Cachard |
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Title |
Estimation Of Viscoelastic Properties Of Vessel Walls Using a Computational Model and Doppler Ultrasound |
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2010 |
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Physics in Medicine and Biology |
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PMB |
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55 |
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12 |
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3557–3575 |
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Human arteries affected by atherosclerosis are characterized by altered wall viscoelastic properties. The possibility of noninvasively assessing arterial viscoelasticity in vivo would significantly contribute to the early diagnosis and prevention of this disease. This paper presents a noniterative technique to estimate the viscoelastic parameters of a vascular wall Zener model. The approach requires the simultaneous measurement of flow variations and wall displacements, which can be provided by suitable ultrasound Doppler instruments. Viscoelastic parameters are estimated by fitting the theoretical constitutive equations to the experimental measurements using an ARMA parameter approach. The accuracy and sensitivity of the proposed method are tested using reference data generated by numerical simulations of arterial pulsation in which the physiological conditions and the viscoelastic parameters of the model can be suitably varied. The estimated values quantitatively agree with the reference values, showing that the only parameter affected by changing the physiological conditions is viscosity, whose relative error was about 27% even when a poor signal-to-noise ratio is simulated. Finally, the feasibility of the method is illustrated through three measurements made at different flow regimes on a cylindrical vessel phantom, yielding a parameter mean estimation error of 25%. |
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BCNPCL @ bcnpcl @ BBC2010 |
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1312 |
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