Abstract: Explainability methods have been widely used to provide insight into the decisions made by statistical models, thus facilitating their adoption in various domains within the industry. Counterfactual explanation methods aim to improve our understanding of a model by perturbing samples in a way that would alter its response in an unexpected manner. This information is helpful for users and for machine learning practitioners to understand and improve their models. Given the value provided by counterfactual explanations, there is a growing interest in the research community to investigate and propose new methods. However, we identify two issues that could hinder the progress in this field. (1) Existing metrics do not accurately reflect the value of an explainability method for the users. (2) Comparisons between methods are usually performed with datasets like CelebA, where images are annotated with attributes that do not fully describe them and with subjective attributes such as ``Attractive''. In this work, we address these problems by proposing an evaluation method with a principled metric to evaluate and compare different counterfactual explanation methods. The evaluation method is based on a synthetic dataset where images are fully described by their annotated attributes. As a result, we are able to perform a fair comparison of multiple explainability methods in the recent literature, obtaining insights about their performance. We make the code public for the benefit of the research community.

Abstract: Background and study aims Artificial intelligence is currently able to accurately predict the histology of colorectal polyps. However, systems developed to date use complex optical technologies and have not been tested in vivo. The objective of this study was to evaluate the efficacy of a new deep learning-based optical diagnosis system, ATENEA, in a real clinical setting using only high-definition white light endoscopy (WLE) and to compare its performance with endoscopists. Methods ATENEA was prospectively tested in real life on consecutive polyps detected in colorectal cancer screening colonoscopies at Hospital Clínic. No images were discarded, and only WLE was used. The in vivo ATENEA's prediction (adenoma vs non-adenoma) was compared with the prediction of four staff endoscopists without specific training in optical diagnosis for the study purposes. Endoscopists were blind to the ATENEA output. Histology was the gold standard. Results Ninety polyps (median size: 5 mm, range: 2-25) from 31 patients were included of which 69 (76.7 %) were adenomas. ATENEA correctly predicted the histology in 63 of 69 (91.3 %, 95 % CI: 82 %-97 %) adenomas and 12 of 21 (57.1 %, 95 % CI: 34 %-78 %) non-adenomas while endoscopists made correct predictions in 52 of 69 (75.4 %, 95 % CI: 60 %-85 %) and 20 of 21 (95.2 %, 95 % CI: 76 %-100 %), respectively. The global accuracy was 83.3 % (95 % CI: 74%-90 %) and 80 % (95 % CI: 70 %-88 %) for ATENEA and endoscopists, respectively. Conclusion ATENEA can accurately be used for in vivo characterization of colorectal polyps, enabling the endoscopist to make direct decisions. ATENEA showed a global accuracy similar to that of endoscopists despite an unsatisfactory performance for non-adenomatous lesions.

Abstract: : Edge-based color constancy methods make use of image derivatives to estimate the illuminant. However, different edge types exist in real-world images such as material, shadow and highlight edges. These different edge types may have a distinctive influence on the performance of the illuminant estimation. Therefore, in this paper, an extensive analysis is provided of different edge types on the performance of edge-based color constancy methods. First, an edge-based taxonomy is presented classifying edge types based on their photometric properties (e.g. material, shadow-geometry and highlights). Then, a performance evaluation of edge-based color constancy is provided using these different edge types. From this performance evaluation it is derived that specular and shadow edge types are more valuable than material edges for the estimation of the illuminant. To this end, the (iterative) weighted Grey-Edge algorithm is proposed in which these edge types are more emphasized for the estimation of the illuminant. Images that are recorded under controlled circumstances demonstrate that the proposed iterative weighted Grey-Edge algorithm based on highlights reduces the median angular error with approximately $25\%$. In an uncontrolled environment, improvements in angular error up to $11\%$ are obtained with respect to regular edge-based color constancy.