Publicacions CVC -- Edit Record

	Publicacions CVC Home \| Show All \| Simple Search \| Advanced Search \| Add Record \| Import	You must login to submit this form! Login Quick Search: Field: contains: ...
	Edit the following record:

Author	...				is Editor
Title	...			Type
Year	...	Publication	...	Abbreviated Journal	...
Volume	...	Issue	...	Pages	...
Keywords	...
Abstract	PURPOSE: Personalized computational simulations of the heart could open up new improved approaches to diagnosis and surgery assistance systems. While it is fully recognized that myocardial fiber orientation is central for the construction of realistic computational models of cardiac electromechanics, the role of its overall architecture and connectivity remains unclear. Morphological studies show that the distribution of cardiac muscular fibers at the basal ring connects epicardium and endocardium. However, computational models simplify their distribution and disregard the basal loop. This work explores the influence in computational simulations of fiber distribution at different short-axis cuts. METHODS: We have used a highly parallelized computational solver to test different fiber models of ventricular muscular connectivity. We have considered two rule-based mathematical models and an own-designed method preserving basal connectivity as observed in experimental data. Simulated cardiac functional scores (rotation, torsion and longitudinal shortening) were compared to experimental healthy ranges using generalized models (rotation) and Mahalanobis distances (shortening, torsion). RESULTS: The probability of rotation was significantly lower for ruled-based models [95% CI (0.13, 0.20)] in comparison with experimental data [95% CI (0.23, 0.31)]. The Mahalanobis distance for experimental data was in the edge of the region enclosing 99% of the healthy population. CONCLUSIONS: Cardiac electromechanical simulations of the heart with fibers extracted from experimental data produce functional scores closer to healthy ranges than rule-based models disregarding architecture connectivity.
Address	...
Corporate Author	...			Thesis
Publisher	...	Place of Publication	...	Editor	...
Language	...	Summary Language	...	Original Title	...
Series Editor	...	Series Title	...	Abbreviated Series Title	...
Series Volume	...	Series Issue	...	Edition	...
ISSN	...	ISBN	...	Medium	...
Area	...	Expedition	...	Conference	...
Notes	...			Approved	yes no
Location
Call Number	...			Serial
Marked	yes no	Copy		Selected	yes no
User Keys	...
User Notes	...			User File	...
User Groups	...			Cite Key	...
Related	...
File
URL	...			DOI	...
	Online publication. Cite with this text: ...

Location Field:	my name & email address

Home

SQL Search | Library Search | Show Record | Extract Citations

Help