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Bronchoscopists use X‐ray fluoroscopy to guide bronchoscopes to the lesion to be biopsied without any kind of incisions. Reducing exposure to X‐ray is important for both patients and doctors but alternatives like electromagnetic navigation require specific equipment and increase the cost of the clinical procedure. We propose a guiding system based on the extraction of airway centers from intra‐operative videos. Such anatomical landmarks could be matched to the airway centerline extracted from a pre‐planned CT to indicate the best path to the lesion. We present an extraction of lumen centers from intra‐operative videos based on tracking of maximal stable regions of energy maps.
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